An Overview of Sermorelin Acetate And Human Growth Hormone

Sermorelin is a substance known as a secretagogue, meaning it causes the release of a hormone in the body. In this case, it causes the pituitary gland to increase human growth hormone production. Therefore, it is a veritable "growth hormone releasing hormone" (GHRH). It stimulates the pituitary gland to naturally make more HGH.

Once the increased growth hormone comes from the pituitary gland, it stimulates the liver to convert it into insulin growth factor (IGF-1). This results in an increase in metabolism and new cell growth within the human body's bones and organs.

Sermorelin Acetate GHRH has been approved for increasing growth hormone levels in children who are deficient in its production. It is an on-label indication and FDA approved for this indication.

In adults, using it to increase growth hormone and IGF-1 levels is an off-label use of the drug. This means it can be prescribed by physicians who determine an indication to be appropriate, but it was not cleared by the FDA specifically for this purpose.

In adults, what effects does Sermorelin treatment have on the body?

繚 Increases lean body muscle mass development through new muscle cells. It doesn't just hypertrophy existing muscle cells, it actually helps make new ones.

繚 Reduces bodyfat

繚 Increases vitality and energy

繚 Increases human endurance

繚 Increases strength

繚 Speeds up wound healing

繚 Strengthens the cardiovascular system

繚 Makes sleep quality better

繚 Benefits the immune system

繚 Ramps up IGF-1 production

繚 Increases and strengthens the mineralization of bones, hence improving bone density.

繚 Stimulates the growth of all internal organs (not the brain)

Interestingly, Sermorelin essentially performs the same function as treatment with HGH itself, just as a production stimulant. Sermorelin is on 29 amino acids, while HGH is larger with 191 amino acids.

So why is Sermorelin preferable? The reason is cost. It's less than one half the cost of treatment with Sermorelin as it is with Recombinant Human Growth Hormone Therapy. Also, Semorelin can be prescribed for unlabeled use, but recombinant HGH can not be prescribed for any unlabeled indication.

Some health food stores will try and sell different secretagogues over the counter, but they are typically just a few amino acids with unpredictable and intermittent release of HGH. There is no specific receptor process in the pituitary gland. There can be kidney problems with high doses. Sermorelin starts its action in a highly specific manner with receptors on the pituitary.

Treatment with Sermorelin is regulated at the level of the pituitary by negative feedback so that it is very difficult to overdose on it. HGH treatment, on the other hand, is not subject to this feedback and may have significant complications. Sermorelin is administered by subcutaneous injection. Typically it's administered once a day prior to bedtime. The time of dosing is important. The duration of treatment will vary depending on what it's being used to treat.